Bourke Street is now blocked between Swanston and Russell streets, and people are being advised to avoid the area.
Two men shopping in the area told the ABC they saw a man throw what they thought to be a bomb into his auto.
Mr Clayton said investigators did not believe there were any other assailants.
One of the officers then shot the man and he collapsed to the ground clutching his chest, the video showed.
A small number of people have been treated for stab wounds.
The incident occurred on a section of the busy street that is closed to traffic.
Two police officers arrive nearly instantly to find a blue utility vehicle ablaze, with flames shooting high into the air.
Members of the public who witnessed the event and wish to make a statement are asked to attend Melbourne West Police Station at 313 Spencer Street, Melbourne. And that the area has been cordoned off.
"Because he was on his stomach, they turned him over to see if he's all right, he was still alive", the witness, Markel Villasin, told Australian Associated Press. Most sat in three rows of chairs, before being called to one of six tables set up by police. Police response was swift and overwhelming.
Shanann Watts' body was later discovered on the property of an oil and natural gas company that Christopher Watts had worked for. Chris Watts and his attorneys have reached a plea deal in the highly-watched murder case out of Frederick.
If you've made some progress in Red Dead Redemption 2 but your camp feels strangely empty, you may be affected by a bug. I got to know each member of my gang in depth thanks to the game's new, simple, yet intuitive dialogue systems.
WTI stays offered after the EIA reported another build in USA crude oil stockpile, this time by 5.783 M barrels during last week. US gasoline futures are also trading in bear market territory , down almost 28 percent from their 52-week high.
Gregory's two friends, both 17-years-old, are facing charges of being accessories to a crime after the fact, authorities said. Ramos was charged Sunday with first-degree premeditated murder and is now being held in a juvenile detention center.
It's all going a bit wrong for Klopp's side and one Liverpool fan ideal summed up all the issues from the game in one tweet. The home side were rewarded for their early pressure in the 23rd minute, when Marin's corner was headed in by Milan Pavkov .
Djokovic's dominant run ended on Sunday when he was beaten 7-5, 6-4 by Russian Kharen Khachanov in the Paris Masters final. Nadal was spotted leaving hospital with his right ankle in a bandage following surgery on Monday.
That nearly certainly wouldn't be the end of this story, but it's the beginning of a new , fraught chapter. The nationwide protest is being organized by a coalition of hundreds of public interest organizations.
Lingard will now hope to start when Manchester United take on Manchester City in a local derby at the Etihad on Sunday. Juve fans have little love for Mourinho after his three-year stint managing bitter rival Inter Milan.
President Trump has abruptly announced on Twitter that Jeff Sessions is no longer the United States attorney general . Sessions said that he did not think he should lead the investigation since he had been a Trump campaign surrogate.
All the Ways Democrats Made History on Tuesday
House of Representatives, makes history as the first woman and first African-American elected to represent the district. There was also an historic gender gap that showed women more supportive of Democrats than Republicans .
Trump administration moves to curb migrants' asylum claims
Administration officials have said existing U.S. asylum rules encouraged illegal immigration and bogged down legitimate claims. Officials have turned away asylum seekers at border crossings because of overcrowding, telling them to return later.
Protect Mueller protests are erupting across the country
He described the president as lawless and corrupt. "I'm concerned Rod Rosenstein will no longer be overseeing the probe". White House adviser Kellyanne Conway is setting the record straight about Attorney General Jeff Sessions' resignation.
Six people injured in California bar shooting
Witnesses said they had spoken to friends who escaped the shooting, which took place during a popular student night at the bar. Social media reports claim the suspect shot the bouncer before throwing a smoke grenade and firing more shots.
FDA Approves Opioid Drug 1,000 Times Stronger than Morphine
Public Citizen described the drug as "five to 10 times more potent than fentanyl and 1,000 times more potent than morphine". But public advocacy groups were quick to condemn the decision because they fear it will lead to more overdoses.
Santiago Solari says Real Madrid win about players
Bale getting a first goal in eight games added to a sense that things are now clicking under still interim coach Santi Solari . It was a landmark night for Benzema , whose first goal was his 200th for the club.
At Least 78 Students Kidnapped in Cameroon
The video has not been verified, but the AP reports some parents wrote on social media that they recognized their children. No one has yet claimed responsibility for Monday's mass kidnapping. "We shall only release you after the struggle".
Ariana Grande apologises to ex Ricky Alvarez
Davidson went on to describe Grande as a " wonderful, strong person " and wished her all the happiness in the world. This should be the last time we hear about the Ariana Grande-Pete Davidson relationship that was.